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AKT2 (PKB) Beta Antibody
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Catalog# Product Description |
CN0145 PKB beta (AKT2) is a member of the PKB family which is responsive to cell activation. The anti-AKT2 antibody was raised with a peptide derived from the C-terminal sequence of human AKT2 and affinity purified with the same peptide as the affinity matrix. |
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Species
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Rabbit
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Formulation
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250 μg/mL in TBS, 50% glycerol, 0.01% NaN3
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Immunogen
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Human AKT2 C-terminal peptide KLH conjugates
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Purification
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Affinity purified with AKT2-peptide
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Specificity
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The antibody recognizes AKT2 in human and mouse and may cross react with other isoforms of AKT.
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Applications
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ELISA (0.25 - 1.0 μg/mL); WB (0.25 - 1.0 μg/mL)
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Scientific Description
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Protein kinase B or AKT (PKB/AKT) is a serine/threonine kinase. Three highly homologous members of AKT in mammals are PKB alpha (AKT1), PKB beta (AKT2) and PKB gamma (AKT3). This enzyme is involved in important cellular processes such as glucose metabolism, cell proliferation, apoptosis, transcription and cell migration.
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Storage & Stability
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Product is stable for several weeks at 4°C. For extended storage, store product at –20oC. Expiration date is one year from date of shipping if properly stored.
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Product Specific References
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1. Curr. Opin. Cell Biol. 1998. 10(2): 262-267. doi: 10.1038/10026
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